COVID-19和结核病的共感染:来自南印度一家三级护理中心的病例控制研究
Druti Hazra1, Nayana Siddalingaiah1, Nitin Gupta2
1Department of Microbiology, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Karnataka, India.
Journal of family medicine and primary care
|February 16, 2024
概括
与结核病 (TB) 和2019年冠状病毒病 (COVID-19) 共同感染具有独特的临床特征. 较高的上叶参与率和像C反应蛋白这样的高生物标志物表明COVID-19患者的结核病.
科学领域:
- 传染性疾病 传染性疾病
- 肺部病理学 肺部病理学
- 公共卫生 公共卫生
背景情况:
- 冠状病毒疾病2019 (COVID-19) 和结核病 (TB) 是全球重要的健康威胁.
- 与COVID-19和结核病的同时感染可能会使诊断复杂并影响患者的结果.
研究的目的:
- 为了比较COVID-19和结核病共感染的患者与仅患有COVID-19的患者的临床特征和结果.
主要方法:
- 从2020年8月到2022年2月进行了一项回顾性病例控制研究.
- 27名共感染COVID-19-TB的患者与27名仅感染COVID-19的患者进行了匹配.
- 数据分析涉及千平方测试和t测试/曼-惠特尼U测试.
主要成果:
- 结核病-COVID-19联合感染显示,上叶参与率 (44%vs. 7%) 和多叶流液 (22%vs. 4%) 显著增加.
- 在共感染组中,C反应蛋白和费里丁的中位水平显著升高.
- 一个P值<0.05表明了统计学意义.
结论:
- 胸部放射学发现和高生物标志物 (C-反应蛋白,费里丁) 可以帮助怀疑COVID-19患者的结核病,反之亦然.
- 早期发现共感染对于适当的管理和改善患者的治疗结果至关重要.
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