一种深度学习模型的开发和多机构验证,用于在排泄囊尿管回流图上对囊尿管回流的分级:一项回顾性多中心研究
Zhanchi Li1, Zelong Tan2, Zheyuan Wang3
1Shanghai Jiao Tong University School of Medicine, Shanghai, China.
EClinicalMedicine
|February 16, 2024
概括
一个新的深度学习模型,Deep-VCUG,提高了在排空囊回血图 (VCUG) 上等级囊回血 (VUR) 的可靠性. 这种人工智能工具表现出高准确度,并协助临床医生进行VUR分级.
科学领域:
- 医疗成像医学成像
- 人工智能在医学中的应用
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
背景情况:
- 排空囊回形图 (VCUG) 是诊断囊回流 (VUR) 的标准.
- 目前从VCUG获得的VUR等级是主观的,缺乏可靠性.
- 需要提高VUR分级的客观性和准确性.
研究的目的:
- 开发一个深度学习模型,Deep-VCUG,用于客观的VUR评分.
- 在VCUG图像上提高VUR分级的可靠性.
- 将模型的表现与临床医生进行比较.
主要方法:
- 使用1948年VCUG图像 (内部和外部数据集) 的回顾性研究.
- 使用ResNet 101和投票方法开发了一个集体学习模型 (Deep-VCUG).
- 使用AUC,灵敏度,特异性和准确度评估性能;与临床医生相比.
主要成果:
- 深度VCUG在单边 (0.962内部,0.944外部) 和双边 (0.960内部,0.924外部) VUR分级方面实现了高AUC.
- 该模型在VUR分类中表现优于单个模型和临床医生.
- 在深度VCUG协助下,临床医生的表现显著改善.
结论:
- 深度VCUG提供了一个可泛化,客观和准确的VUR分级方法.
- 该模型有效地协助临床医生对VUR进行分级,提高了适用性.
- 深度VCUG代表了VUR诊断和管理的重大进步.
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