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Updated: Jul 3, 2025

Author Spotlight: Exploring Intrinsically Disordered Protein Dynamics Through NMR Relaxation Experiments
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Author Spotlight: Exploring Intrinsically Disordered Protein Dynamics Through NMR Relaxation Experiments

Published on: November 1, 2024

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设计内在无序的蛋白质,这些蛋白质在较低的临界溶液温度下经历相变

Xiangze Zeng1, Chengwen Liu2, Martin J Fossat1

  • 1Department of Biomedical Engineering and Center for Science & Engineering of Living Systems (CSELS), Washington University in St. Louis, St. Louis, MO 63130, USA.

APL materials
|February 16, 2024
PubMed
概括

研究人员设计了具有特定热响应行为的新型内在无序蛋白 (IDP) 序列. 使用蒙特卡洛模拟和遗传算法,他们成功地创建了表现出较低临界溶液温度 (LCST) 阶段行为的IDP.

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