多发性硬化症风险与饮食中的抗炎/抗炎食物摄入量和饮食多样性之间的关联:一项病例对照研究
Alireza Hatami1, Maryam Ahmadi-Khorram1, Fatemeh Keykhaei1
1Department of Nutrition, School of Medicine, Mashhad University of Medical Sciences, Mashhad 91779-48564, Iran.
Clinical nutrition research
|February 16, 2024
概括
富含炎症性食物的饮食增加了多发性硬化症 (MS) 的风险. 促炎/抗炎食物摄入评分 (PAIFIS) 可以预测MS,强调饮食.
科学领域:
- 营养科学 营养科学
- 神经学 神经学
- 流行病学 流行病学
背景情况:
- 炎症和促炎症饮食是多发性硬化症 (MS) 的潜在危险因素.
- 了解饮食对MS风险的影响对于预防和管理策略至关重要.
研究的目的:
- 调查饮食炎症潜力与MS风险之间的关联.
- 评估饮食多样性在MS发展中的作用.
主要方法:
- 一项基于医院的病例控制研究,涉及197名多发性硬化症患者和200名健康对照.
- 评估饮食摄入量使用160项的半定量食物频率问卷.
- 计算促炎/抗炎食物摄入评分 (PAIFIS) 和饮食多样性评分 (DDS).
主要成果:
- 与健康个体相比,MS患者的PAIFIS显著更高 (p = 0.001).
- 较高的PAIFIS与MS风险增加显著相关 (几率比,1.002;95% CI,1.001-1.004;p = 0.001).
- 在这项研究中,饮食多样性评分 (DDS) 没有显示出与MS风险的显著关联.
结论:
- 反映饮食炎症的PAIFIS可以作为多发性硬化症风险的预测指数.
- 饮食中的炎症潜力是与MS相关的重要因素.
- 需要进一步的研究来证实这些发现并探索临床影响.
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