接种COVID-19疫苗后的急性腹部:系统性审查
Nelson Luis Cahuapaza-Gutierrez1,2, Renzo Pajuelo-Vasquez1,2, Cristina Quiroz-Narvaez1,2
1Facultad de Ciencias de la Salud, Carrera de Medicina Humana, Universidad Científica del Sur, Lima, Perú.
Clinical and experimental vaccine research
|February 16, 2024
概括
急性腹部是2019年新冠肺炎 (COVID-19) 疫苗接种后的一种罕见并发症. 这次对17例病例的审查发现了各种表现,主要与Pfizer-BioNTech疫苗有关,大多数患者在治疗后康复良好.
科学领域:
- 胃肠病学 胃肠病学
- 疫苗学 疫苗学 疫苗学
- 公共卫生 公共卫生
背景情况:
- 冠状病毒病2019 (COVID-19) 疫苗接种已成为全球公共卫生战略.
- 免疫接种后的罕见不良事件需要彻底调查,以确保疫苗的安全性.
- 急性腹部,一个外科紧急情况,已经被事地与COVID-19疫苗接种联系起来.
研究的目的:
- 系统地审查关于COVID-19疫苗接种后急性腹部疫苗的病例报告和系列.
- 描述这些病例的临床和人口特征.
- 评估COVID-19疫苗接种与急性腹部发育之间的关联.
主要方法:
- 通过PubMed,Scopus,EMBASE和Web of Science识别的病例报告和病例系列的系统审查.
- 包括标准侧重于COVID-19疫苗接种后的急性腹部发育;不包括评论,信件和评论.
- 使用乔安娜·布里格斯研究所工具评估了偏见的质量和风险;采用了描述性统计数据.
主要成果:
- 在接种COVID-19疫苗后,确定了17例急性腹部病例,包括尾炎,胰腺炎,分泌炎,胆囊炎和大肠炎.
- 瑞-生物科技 (信使RNA) 疫苗是最常见的 (64.71%),大多数病例发生在第一剂后 (52.94%).
- 所有患者对医疗 (88.34%) 或手术 (11.76%) 治疗反应良好,没有死亡报告.
结论:
- 急性腹部是COVID-19疫苗接种的罕见但显著的潜在并发症,需要在医疗和外科实践中引起注意.
- 确定的病例表明可能存在关联,尽管潜在的机制尚不清楚.
- 建议进行进一步的观察性研究,以更好地了解这种罕见的不良事件.
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