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Updated: Jul 3, 2025

Characterize Disease-related Mutants of RAF Family Kinases by Using a Set of Practical and Feasible Methods
07:49

Characterize Disease-related Mutants of RAF Family Kinases by Using a Set of Practical and Feasible Methods

Published on: July 17, 2019

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新的RAF导向方法可以克服当前的临床限制,并阻止RAS/RAF节点

Rossella Scardaci1, Ewa Berlinska1, Pietro Scaparone1

  • 1Department of Molecular Biotechnology and Health Sciences, Molecular Biotechnology Center, University of Torino, Italy.

Molecular oncology
|February 16, 2024
PubMed
概括

在癌症中准RAS-RAF-MEK-ERK通路至关重要. 新的疗法,如悖论破坏剂和二元抑制剂,旨在克服耐药性和治疗各种RAF变异,为选择有限的患者提供希望.

关键词:
英国皇家空军 (RAF) 的飞机.拉斯拉斯拉斯拉斯拉斯拉斯拉斯拉斯拉斯癌症耐药性 癌症耐药性抑制剂 抑制剂 抑制剂新的治疗方法这是一个悖论性的效应.

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