在急性和复发性类风湿性发烧后的结果
Suchaya Silvilairat1, Artit Sornwai1, Saviga Sethasathien1
1Department of Paediatrics, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
Paediatrics and international child health
|February 16, 2024
概括
复发性类风湿性发烧 (RRF),高三反 (TR) 梯度和扩大的左心室末端透缩维度 (LVEDD) 预测了类风湿性心炎患者需要门手术的情况. 早期识别有助于管理这种残疾状况.
科学领域:
- 心脏病学 心脏病学
- 类风湿病学 类风湿病学
- 儿童心脏病学 儿童心脏病学
背景情况:
- 类风湿性心炎是永久性心脏膜残疾的主要原因,需要了解急性类风湿性发烧 (ARF) 和复发性类风湿性发烧 (RRF) 的结果.
- 确定门手术的预测因素对于管理ARF和RRF患者至关重要.
研究的目的:
- 为了确定诊断为ARF和RRF的患者的门手术的结果.
- 为了确定与此患者队列中需要门手术相关的预测因素.
主要方法:
- 在2006年至2021年期间,对92名被诊断为ARF和RRF的患者进行了回顾性研究.
- 用多变量考克斯比例回归分析来确定门手术的预测因素.
主要成果:
- 临床心炎 (87%) 和心力衰竭 (63%) 是常见的表现. 25%的患者接受了门手术.
- 复发性类风湿性发烧 (HR 7.9),三回梯度≥42 mmHg (HR 6.3) 和LVEDD≥6 cm (HR 8.7) 是门手术的显著预测因素.
结论:
- 在59%的患者中,普雷迪尼索隆治疗减少了膜反的严重程度.
- RRF,升高的TR梯度和增加的LVEDD是ARF/RRF患者门手术的关键预测因素.
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