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Updated: Jun 12, 2026

Combining Peripheral Nerve Grafting and Matrix Modulation to Repair the Injured Rat Spinal Cord
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在限制间隙长度之外:通过可植入的神经引导管道进行外围神经再生

Eugenio Redolfi Riva1,2, Melis Özkan3,4, Estefania Contreras5,6

  • 1The Biorobotic Institute, Scuola Superiore Sant'Anna, Piazza Martiri della Libertà 33, 56127 Pisa, Italy. eugenio.redolfiriva@santannapisa.it.

Biomaterials science
|February 16, 2024
PubMed
概括

神经引导管道为外围神经修复提供了自体移植的替代方案. 优化导管设计和材料对于再生长的神经间隙至关重要,克服当前的局限性.

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Neurogenesis and Regeneration of Nervous Tissue01:15

Neurogenesis and Regeneration of Nervous Tissue

In the CNS, neurogenesis, the birth of new neurons from stem cells, is limited to the hippocampus in adults. In other regions of the brain and spinal cord, neurogenesis is almost non-existent due to inhibitory influences from neuroglia, especially oligodendrocytes, and the absence of growth-stimulating cues. The myelin produced by oligodendrocytes in the CNS inhibits neuronal regeneration. Furthermore, astrocytes proliferate rapidly after neuronal damage, forming scar tissue that physically...