总合成和细胞毒性评价的spirostanol桑素吉托宁的总合成和细胞毒性

Yong Li1,2, Xun Lv3, Jun Liu1,2,4

  • 1State Key Laboratory of Environmental Chemistry and Eco-toxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China. junliu@rcees.ac.cn.

PubMed
概括

这项研究有效地合成了螺旋醇氨酸gitonine,并评估了其对癌症细胞系的细胞毒性活性. 吉托宁衍生物表现出中度至优异的抑制活性,具有影响细胞毒性的特定结构特征.

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