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来自基于环极德的多态形态复合物的客服药物的受控化率及其与分子动态的相关性,通过固态NMR探测

Sudeshna Kundu1, Kenjirou Higashi1, Makoto Takamizawa1

  • 1Graduate School of Pharmaceutical Sciences, Chiba University, Inohana 1-8-1, Chuo-ku, Chiba 260-8675, Japan.

Molecular pharmaceutics
|February 16, 2024
PubMed
概括

将酸 (SA) 封装在环氧德克斯/聚乙烯甘醇 (polypseudorotaxane) 复合物中,提高了其物理稳定性. 与升华率直接相关的分子流动性,在不同的多态形式中有所不同,为药物输送系统设计提供了洞察力.

关键词:
复杂化的复杂化分子动力学分子动力学多形态主义的多态主义.固态NMR光谱学 固态NMR光谱学潜质化 潜质化是一种

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