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2型糖尿病成年人的持续血糖监测:系统性审查和元分析
Milena Jancev1, Tessa A C M Vissers1, Frank L J Visseren1
1Department of Vascular Medicine and Endocrinology, University Medical Center Utrecht, Utrecht, the Netherlands.
Diabetologia
|February 16, 2024
概括
与传统的血糖监测相比,持续的葡萄糖监测 (CGM) 显著改善了2型糖尿病患者的血糖控制. 这一系统性审查强调了HbA1c,范围内的时间和降低葡萄糖变异性的好处.
科学领域:
- 内分泌学 在内分泌学.
- 代谢疾病 代谢疾病
- 糖尿病管理 糖尿病管理
背景情况:
- 持续血糖监测 (CGM) 越来越多地用于2型糖尿病管理.
- 它对血糖控制的影响需要全面评估.
研究的目的:
- 对CGM对2型糖尿病成年人血糖控制的影响进行系统审查和元分析.
- 为了比较CGM (实时和间歇扫描) 与血糖自我监测 (SMBG).
主要方法:
- 从Embase,MEDLINE,科学网络,Scopus和临床试验.gov.gov.的RCT进行系统审查.
- 包括的研究比较了2型糖尿病成年人的CGM (rtCGM或isCGM) 与SMBG.
- 提取了关于HbA1c,范围内的时间 (TIR),范围以下的时间 (TBR),范围以上的时间 (TAR) 和血糖变化的数据.
主要成果:
- 与SMBG相比,使用CGM显著降低了HbA1c -3.43 mmol/mol (-0.31%) 与SMBG相比.
- CGM增加了范围内的时间 (TIR) +6.36%,范围以上的时间 (TAR) 减少了 -5.86%.
- 实时CGM显示了比间歇扫描CGM更大的HbA1c降低的趋势.
结论:
- 在患有2型糖尿病的成年人中,CGM改善了血糖控制.
- 限制包括开放性研究和严重低血糖和并发症的稀缺数据.
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