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在患有Sjögren综合征的患者中,间歇性肺病和相关因素

Gökhan Sargın¹, Huseyin Baygin², Songul Cildag²

¹Department of Rheumatology, Medical Faculty, Aydin Adnan Menderes University, Aydın, Turkey. gokhan_sargin@hotmail.com.

Irish journal of medical science

|February 16, 2024

概括

间歇性肺病 (ILD) 影响8.7%的Sjögren患者.

科学领域:

类风湿病学类风湿病学
肺部病理学肺部病理学
内部医学内部医学

背景情况:

间歇性肺病 (ILD) 是Sjögren综合征 (SjS) 的重要并发症,增加死亡风险.
早期识别ILD及其风险因素对于管理类风湿性疾病至关重要.

研究的目的:

为了调查Sjögren综合征患者ILD的患病率.
确定与SjSILD相关的临床,实验室和成像因素.

主要方法:

一项涉及403名Sjögren综合征患者的横截面队列研究.
临床,实验室,血清学和成像特征的比较,包括肺部受影响和没有肺部受影响的患者.
后勤回归分析以确定肺部参与的风险因素.

主要成果:

8.7%的SjS患者表现出ILD.
独立的ILD风险因素包括老年 (>65岁),雷诺病现象和吸烟.
非特异性间歇性肺炎和常见间歇性肺炎是最常见的ILD类型.

结论:

高龄,吸烟和雷诺现象是SjS患者ILD的重要危险因素.
男性患者的肺部感染率更高,可能是由于吸烟率更高和尼古丁消费时间更长.
年龄,吸烟和ILD严重程度是比炎症或自身抗体更重要的预后指标.

关键词:

相关因素相关因素间歇性肺病间歇性肺病肺部卷入肺部卷入斯约格伦综合征是什么意思

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