对38名被诊断为乳腺癌的男性患者进行临床病理学分析
Seniha Irem Sahin1, Serdar Balci2, Gulnur Guler3
1Department of Pathology and Laboratory Medicine, Division of Anatomic Pathology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.
Breast disease
|February 16, 2024
概括
男性乳腺癌 (MBC) 在老年男性中被诊断出,通常是在晚期的荷尔蒙受体阳性阶段. 这种独特的实体需要特定的临床和病理方法来改善结果.
科学领域:
- 在瘤学瘤学.
- 医学研究 医学研究
背景情况:
- 男性乳腺癌 (MBC) 占所有乳腺癌的1%.
- 有限的认识和查导致晚期诊断和低生存率.
研究的目的:
- 调查男性乳腺癌的预后因素.
- 将这些因素与已确定的参数和患者结果相关联.
主要方法:
- 追溯分析38名男性乳腺癌患者的数据.
- 收集了临床和病理特征.
- 雌激素受体 (ER) 和孕激素受体 (PR) 的阳性评估使用1%和10%的截止值.
主要成果:
- 老年男性更容易发生MBC和状淋巴结转移.
- 侵入性导管癌是主要的组织学类型.
- 所有患者都呈现ER和PR阳性;44.7%的患者患有远程转移,通常发生在骨中.
结论:
- 主要影响老年男性的MBC,在晚期呈现.
- 激素受体阳性和骨转移是特征性的.
- 乳腺癌是一种独特的生物实体,需要量身定制的临床和病理管理.
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