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Updated: Jul 2, 2025

Preparation of Tumor Antigen-loaded Mature Dendritic Cells for Immunotherapy
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对I型树突细胞的STING授权增强了抗瘤免疫力

Jian Wang1,2, Suxin Li1, Maggie Wang1

  • 1Department of Pharmacology, Harold C. Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

Science immunology
|February 16, 2024
PubMed
概括

传统的1型树突细胞 (cDC1s) 对于STING介导的抗瘤免疫是至关重要的. 主体STING在cDC1s中的激活,而不是癌细胞,驱动瘤排斥并与患者的生存相关.

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