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在由于左心病导致的肺高血压中开发和验证诊断名录

Shi Shi¹, Xu Zhu², Iokfai Cheang²

¹National Key Laboratory for Innovation and Transformation of Luobing Theory. Department of Cardiology, the First Affiliated Hospital of Nanjing Medical University, Jiangsu Province Hospital, Nanjing 210029, China; Department of Cardiology, Hai'an People's Hospital, Nantong 226600, China.

Heart & lung : the journal of critical care

|February 16, 2024

概括

一种新型的诺米图准确地预测了使用非侵入性指标的左心病患者的肺高血压. 该工具有助于对这种常见疾病进行早期风险评估.

科学领域:

心脏病学心脏病学
肺部医学肺部医学
医学诊断医学诊断医学诊断

背景情况:

以左心病 (LHD) 为次要的肺高血压 (PH) 是最常见的PH形式.
准确的诊断对于管理LHD相关PH至关重要.

研究的目的:

开发一种用于诊断LHD患者PH的预测性名录模型.
该模型整合了传统的非侵入性检查和特定的检测指标.

主要方法:

对361名经过右心导管治疗 (RHC) 的LHD患者进行了回顾性分析.
患者被分为培训 (70%) 和验证 (30%) 队列.
拉索回归和多变量逻辑回归用于模型构建.

主要成果:

48.5%的患者被诊断出患有PH-LHD.
确定了关键预测因素:静止心率,NYHA功能类,红细胞分布宽度,RV终端-透气直径和心声图肺动脉静脉压.
命名图显示出强烈的诊断歧视 (AUC = 0.866) 和验证队列中的校准.

结论:

为PH-LHD开发了一种非侵入性名谱.
诺米图表显示出出色的诊断价值和临床适用性.
它可以更准确地评估LHD患者的PH风险.

关键词:

这个名字叫做Nomogram.非侵入性诊断是一种非侵入性诊断.由于左心病导致的肺高血压.

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