发展用于管理和治疗阿尔茨海默病的治疗干预措施
Faizan Ahmad1, Anik Karan2, Rashi Sharma3
1Department of Medical Elementology and Toxicology, Jamia Hamdard University, Delhi, India.
Ageing research reviews
|February 16, 2024
概括
本综述探讨了新的阿尔茨海默病 (AD) 治疗方法,包括已批准的药物,如阿杜卡努马布和莱卡内马布,以及免疫疗法,疫苗和新兴策略. 它涵盖了AD管理的当前,未来和非药物干预措施.
科学领域:
- 神经科学是一个神经科学.
- 药理学 药理学是指药理学的学科.
- 老年学是指老年学的学科.
背景情况:
- 阿尔茨海默氏症 (AD) 呈现出各种影响认知和行为的症状.
- 目前的治疗策略旨在减缓疾病的进展和控制症状.
研究的目的:
- 审查阿尔茨海默病 (AD) 的新疗法方法.
- 强调最近批准和正在研究的治疗方法,包括免疫疗法,疫苗和新兴策略.
主要方法:
- 关于已批准的,临床的和临床前的AD疗法的综合文献综述.
- 讨论新的策略,如基因疗法,纳米医学和精密医学.
- 包括非标签药物使用和非药物干预措施用于AD症状管理.
主要成果:
- 阿杜卡努马布 (Aducanumab) 和莱卡内马布 (Lecanemab) 是最近FDA批准的针对粉样质斑块的进展.
- 积极和被动免疫疗法,疫苗和干细胞疗法正在临床研究中.
- 临床前研究探索基因编辑 (CRISPR/Cas9),纳米医药和AD的反感性疗法.
结论:
- 对阿尔茨海默病的治疗干预措施的广泛范围正在调查中,从已批准的药物到未来的方法.
- 在阿尔茨海默病治疗方面仍然存在重大挑战,需要继续进行研究和开发.
- 结合药理和非药理方法的综合管理策略对于AD患者至关重要.
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