扩散MRI标志着亨廷顿病zQ175DN小鼠模型中纤维完整性的渐进性改变

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Updated: Jul 2, 2026

Diffusion Tensor Magnetic Resonance Imaging in the Analysis of Neurodegenerative Diseases
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Diffusion Tensor Magnetic Resonance Imaging in the Analysis of Neurodegenerative Diseases

Published on: July 28, 2013

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Nicholas Vidas-Guscic1, Joëlle van Rijswijk1, Johan Van Audekerke1

  • 1Bio-Imaging Lab, University of Antwerp, Antwerp, Belgium; μNeuro Center for Excellence, University of Antwerp, Antwerp, Belgium.

Neurobiology of disease
|February 16, 2024
PubMed
概括

这项研究表明,先进的MRI分析 (FBA) 在亨廷顿病 (HD) 鼠标模型中检测到早期白质变化,优于传统方法. 这些发现为跟踪疾病进展和治疗有效性提供了潜在的生物标志物.

关键词:
基于固定值的分析.亨廷顿病就是亨廷顿病.纵向的 纵向的 纵向的神经退行发生神经退行.神经纤维纤维是一种神经纤维.临床前 临床前

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