超声波设置对NiTi植入物的温度变化的影响
Shaye M Tiell1, Manaswini Chennoju1, Brian L Davis1
1Cleveland State University, Cleveland, OH, USA.
Medical engineering & physics
|February 16, 2024
概括
治疗性超声波可以通过提高其温度来激活- (NiTi) 植入物的形状变化. 超声波功率显著影响温度变化,这是设计改变形状的骨科设备的关键因素.
科学领域:
- 生物医学工程 生物医学工程
- 材料科学 材料科学 材料科学
- 医学物理 医学物理
背景情况:
- 形状记忆合金 (SMA),特别是- (NiTi),为先进的生物医学设备提供独特的改变形状的能力.
- 虽然NiTi的超弹性是众所周知的,但其热诱导的形状转换是最小侵入性植入物的关键,可以在植入后调整形状.
- 治疗性超声波呈现了一种新的非侵入性方法,通过快速加热通过皮肤触发NiTi的马氏体热弹性转变.
研究的目的:
- 研究治疗超声波参数与NiTi标本温度变化之间的关系.
- 为了确定不同的超声波频率和功率设置如何影响NiTi样本的温度升高.
- 评估利用超声波对基于NiTi的医疗器械进行受控热激活的可行性.
主要方法:
- 两个NiTi标本被对应于超声波应用,每个应用时间为2分钟.
- 实验使用了Sonicator 740和Dynatron 150治疗性超声波设备.
- 在32个试验中使用了不同的低频和高频和功率设置,基线温度保持在室温 (23.0 ± 1.7°C).
主要成果:
- 这两种治疗性超声波设备都成功地提高了NiTi样本的温度 (Sonicator 740: 2.2 ± 2.4°C;Dynatron 150: 1.5 ± 1.15°C).
- 统计分析显示,Dynatron 150的低功率和高功率设置之间的平均温度变化存在显著差异 (ANCOVA; p = 0.013).
- 这些发现证实,治疗性超声波可以诱导NiTi的可测量的温度升高.
结论:
- 治疗性超声波提供了一种有效的手段,可以快速提高NiTi植入物温度.
- 超声波功率是温度变化的关键决定因素,必须在需要控制形状重新配置的骨科植入物设计时考虑.
- 这种方法为医疗应用中NiTi植入物在现场调整提供了一个有前途的方法.
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