相关实验视频
Updated: Jul 2, 2025

08:28
Development of an In Vitro Ocular Platform to Test Contact Lenses
Published on: April 6, 2016
10.6K
在正常的中国成年人中持续24小时内眼压监测,使用一种新型的隐形眼镜传感器系统
Yuning Zhang1, Yifan Wei1, Ching Hymn Christopher Lee2
1State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangdong Provincial Clinical Research Center for Ocular Diseases, Guangzhou, China.
The British journal of ophthalmology
|February 16, 2024
概括
正常的中国成年人表现出稳定的24小时眼内压力 (IOP) 节奏,夜间IOP较低. 内压平均值随着年龄的增长而增加,变化与年龄和男性性别相关.
科学领域:
- 眼科医生 眼科 眼科
- 身体生理学 身体生理学
- 生物医学工程 生物医学工程
背景情况:
- 眼内压力 (IOP) 呈现日间变化,对眼睛健康至关重要.
- 准确的,持续的IOP监测对于理解这些节奏至关重要.
- 新型隐形眼镜传感器系统 (CLS) 提供了实时IOP测量的潜力.
研究的目的:
- 为了研究正常中国成年人的生理性眼内血压 (IOP) 节奏.
- 评估一种新型隐形眼镜传感器系统 (CLS) 的有效性,用于连续24小时的IOP监测.
- 分析与白天和夜间周期,性别和年龄相关的IOP模式.
主要方法:
- 59名正常的中国成年人接受了24小时内血压监测,使用了一种新型的CLS.
- 进行了24小时内血压平均值,峰值,低谷,波动和眼内压力外流 (MAPE) 的平均幅度的描述性分析.
- 分析了白天,夜间和睡眠时间的数据,并通过性别和年龄组 (<30岁和≥30岁) 进行了比较.
主要成果:
- 与白天相比,夜间IOP显示了较低的峰值,较高的低谷,以及较小的波动/MAPE.
- 在右眼和左眼之间没有观察到IOP参数的显著差异.
- 男性受试者和30岁或以上的受试者分别表现出更大的IOP波动和更高的IOP平均值.
结论:
- 新的CLS在正常的中国成年人中提供稳定,连续24小时的IOP数据.
- 平均内血压水平在白天和晚上之间是可比的,有分散的缩期和浴期.
- 增加年龄和男性性别与更高的平均内血压和更大的内血压变化有关.
相关概念视频
Glaucoma: Overview
570
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
570
Open Angle Glaucoma: Treatment
449
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
449
Angle Closure Glaucoma: Treatment
498
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
498

