新生儿感染的风险因素 肠道功能不全的新生儿感染的风险因素
Dana Wu1, Rhonda Van Oerle2, Andrea Martinez3
1Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada.
Journal of pediatric surgery
|February 16, 2024
概括
患有肠衰竭的新生儿往往会患上感染,早产和复杂的胃分裂是关键的危险因素. 虽然感染会影响生长,但在本研究中,感染并没有显著改变体重增加的轨迹.
科学领域:
- 新生儿科学 新生儿科学
- 儿科手术 儿科手术
- 传染性疾病 传染性疾病
背景情况:
- 患有肠衰竭 (IF) 的新生儿面临着来自中央静脉接入和手术的重大感染风险.
- 在IF的感染可以导致全身炎症,败血症和生长障碍.
- 预防策略对于管理FI相关感染至关重要.
研究的目的:
- 确定新生儿感染IF的风险因素.
- 评估感染对这一脆弱人群生长的影响.
- 为制定有针对性的预防策略提供信息.
主要方法:
- 在86名患有FI的新生儿 (2018-2022) 进行了回顾性比较研究.
- 分析了临床数据,肠道病理,营养和生长.
- 使用曼-惠特尼和克鲁斯卡尔-瓦利斯测试比较感染组 (血液,其他,没有)
主要成果:
- 59%的婴儿患有感染;22%患有血流感染 (BSI),37%患有其他感染 (OI).
- 感染与较低的妊娠年龄,出生体重和口腔口腔的存在有关.
- 所有患有复杂胃的婴儿都感染了感染;生长 (体重增加) 低于最佳水平,但在各组中相似.
结论:
- 在诊断后不久的IF新生儿中,感染很常见.
- 关键的危险因素包括早产,复杂的胃,以及口腔的存在.
- 虽然生长通常不理想,但感染并没有显著影响体重增加轨迹.
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