世界卫生组织2022年分类更新:乳头脏细胞癌的放射和病理特征
Luyao Shen1, Luke Yoon1, Patrick C Mullane2
1Department of Radiology, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, California 94305, USA.
Academic radiology
|February 16, 2024
概括
新定义的乳头性细胞癌 (pRCC) 在成像上经常以低血管,固体质的形式出现. 这些发现支持开发一种非侵入性评分来识别这种惰的癌症,有助于积极监测策略.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 放射学 放射学是一门学科.
- 在瘤学瘤学.
背景情况:
- 世界卫生组织 (WHO) 2022年更新引入了细胞癌亚型的新分类.
- 乳头细胞癌 (pRCC) 是一种重要的亚型,需要更新诊断标准.
- 了解PRCC的成像和病理特征对于准确的诊断和管理至关重要.
研究的目的:
- 根据最新的世卫组织2022年分类,对乳头细胞癌 (pRCC) 的成像和病理特征进行表征.
- 为了将成像发现与新定义的pRCC的病理数据相关联.
- 探索pRCC的非侵入性诊断评分的潜力.
主要方法:
- 在87名患者中对93例病理确认的PRCC病例进行了回顾性分析.
- 使用标准化词汇对治疗前CT或MRI成像进行审查.
- 影像检测结果与外科病理学和临床随访数据的相关性.
主要成果:
- 大多数pRCC呈现为固体 (83%),周边很好,低血管 (99%) 质.
- 一个pRCC子组表现出囊性特征,包括波斯尼亚人IIF类 (4例) 和IV类 (12例).
- 病理学显示主要是低度 (68%级1-2) 和局部 (90% ≤pT2b) 瘤,没有类或类特征.
结论:
- 乳头性细胞癌通常表现为一个低血管性,周围的,固体的质.
- 一小部分的PRCC可能以囊性病变的形式出现,包括波斯尼亚克IIF类亚型.
- 这些成像和病理特征可以为开发PRCC的非侵入性概率得分提供信息,支持积极监测.
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