饮食维生素B1摄入量与老年人认知功能之间的关联:一个横截面研究
Weiai Jia1, Hemei Wang1, Chao Li1
1Department of Anesthesiology, The Fourth Hospital of Hebei Medical University, NO.12, JianKang Road, Shijiazhuang, 050011, Hebei, People's Republic of China.
Journal of translational medicine
|February 16, 2024
概括
饮食中摄入更多的维生素B1 (胺) 与60岁以上成年人更好的认知功能有关. 这项研究表明,胺可能在老年人群中起到维持大脑健康的作用.
科学领域:
- 营养科学 营养科学
- 神经科学是一个神经科学.
- 老年学是指老年学的学科.
背景情况:
- 认知能力下降是老年人群的一个重大问题.
- 饮食因素,如维生素B1 (胺),正在研究它们在认知健康中的作用.
研究的目的:
- 检查饮食维生素B1摄入量与老年人认知功能之间的关联.
- 为了确定胺摄入量是否与特定的认知领域相关,如处理速度,执行功能和记忆.
主要方法:
- 利用了2011-2014年国家健康和营养检查调查 (NHANES) 的数据.
- 包括2422名60岁及以上的参与者.
- 使用数字符号替换测试 (DSST),动物流利性测试 (AFT) 和CERAD子测试评估认知功能;从饮食回忆中摄入维生素B1;使用多变量线性回归分析.
主要成果:
- 较高的维生素B1摄入量与在DSST,AFT和全球认知得分上更好的表现显著相关 (P<0.001).
- 与最低四分位数相比,维生素B1摄入的最高四分位数与DSST (β = 2.23) 和全球认知z-score (β = 0.09) 有积极的关联.
- 在饮食维生素B1摄入量和认知功能得分之间观察到线性关系.
结论:
- 饮食中增加的维生素B1摄入量与老年人的认知功能增强有关.
- 研究结果表明,胺可能是一个可修改的饮食因素,用于支持老年人的认知健康.
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