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Updated: Jul 2, 2025

In Vitro and In Vivo Detection of Mitophagy in Human Cells, C. Elegans, and Mice
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一个可诱导的线粒体特定蛋白质降解系统 in vivo

Swastika Sanyal1, Anna Kouznetsova2, Lena Ström2

  • 1Karolinska Institutet, Department of Biosciences and Nutrition, Neo, Hälsovägen 7c, 141 83, Huddinge, Sweden. swastika.sanyal@ki.se.

Nature communications
|February 16, 2024
PubMed
概括

研究人员使用Mesoplasma florum Lon (mf-Lon) 蛋白酶开发了一种新的诱导性线粒体特异性蛋白质降解系统. 这种系统可以对线粒体蛋白质进行选择性分析,即使是具有双局部化的蛋白质,在酵母和人体细胞中.

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