在成人和儿童中,COVID后症状的自然过程
Aya Sugiyama1, Toshiro Takafuta2, Tomoki Sato2
1Department of Epidemiology Infectious Disease Control and Prevention, Graduate School of Biomedical and Health Sciences, Hiroshima University, 1-2-3, Kasumi, Minami-ku, Hiroshima-shi, Hiroshima-ken, 734-8551, Japan.
Scientific reports
|February 16, 2024
概括
后COVID条件影响许多幸存者,症状持续长期,特别是在成年人中. 风险因素包括年龄,性别,糖尿病,三角洲变种感染和吸烟,但不是接种疫苗.
科学领域:
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 全球超过2亿人经历了持续的COVID后疾病.
- 这些长期症状的持续时间和风险因素围绕着不确定性.
- 这项研究调查了日本队列中COVID后的情况.
研究的目的:
- 为了确定后COVID症状的患病率和持续时间.
- 确定持续超过三个月且影响日常生活的症状的危险因素.
- 分析疫苗接种史和COVID后情况之间的关联.
主要方法:
- 在广岛,对2421名COVID-19幸存者 (成人和儿童) 进行了问卷调查.
- 卡普兰-梅尔法说明了症状的流行程度和持续时间.
- 多变量逻辑回归确定了长期症状的危险因素.
主要成果:
- 首次COVID后症状的发病率在成人中为78.4%,在儿童中为34.6%.
- 一年后,症状发生率降至31.0% (成人) 和6.8% (儿童).
- 症状>3个月的独立风险因素包括年龄,女性性别,糖尿病,三角洲变种感染和吸烟;接种疫苗没有显著的关联.
结论:
- 后COVID疾病很普遍,并且可以长期存在,特别是在成年人中.
- 特定的人口和临床因素增加了长期症状的风险.
- 疫苗接种状态似乎没有影响这个队列中患上COVID后疾病的可能性.
相关概念视频
Stages of Infection
56.4K
Stages of infection describe what happens to a susceptible host once a pathogen invades the human body. The stages of infection are incubation, prodromal, illness, stage of decline, and convalescence. The incubation stage is the period from exposure to a pathogen until symptoms start. The infected person is unaware of impending illness as the pathogens grow and multiply within the body. The duration may vary depending on the type of infection. The incubation period of measles averages ten to...
56.4K
COPD: Pathogenesis and Clinical Features
273
Chronic obstructive pulmonary disease (COPD) is a group of lung conditions that progressively worsen over time, including chronic bronchitis and emphysema. This cluster of diseases collectively leads to a gradual and irreversible decline in lung function over time.
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
273
Pulmonary Cycle: Exhalation
1.6K
In terms of human respiration, the act of expelling air, known as exhalation (or expiration), operates on the principle of pressure gradients. During expiration, the pressure within the lungs exceeds that of the surrounding atmosphere. Under normal conditions, quiet breathing involves passive exhalation and is free of muscular contractions. This is because the exhalation process is driven by the natural elastic recoil of the lungs and chest wall, both of which have an inherent tendency to...
1.6K
Classification of Illness
7.5K
The meaning of illness is individualized to each person who experiences an alteration in health. In contrast, disease is a medical term indicating a pathological change in the structure and function of the body or mind. It is a condition that has specific symptoms and boundaries.
An illness is a response to a disease in which the person's level of functioning is changed compared with a previous level. The general classification of illness includes acute and chronic.
Acute illness is severe...
An illness is a response to a disease in which the person's level of functioning is changed compared with a previous level. The general classification of illness includes acute and chronic.
Acute illness is severe...
7.5K
Pneumonia II: Pathophysiology
272
The pathophysiology of pneumonia involves the following steps:
272
Asthma-III: Symptoms and Complications
2.5K
Asthma, a common chronic respiratory condition, is classified considering the frequency and severity of symptoms alongside lung function impairment. Understanding this classification is essential for appropriate treatment and management. Here's a detailed look at the classification of asthma and its clinical features and complications:
Classification of Asthma
Classification of Asthma
2.5K


