作为重大创伤患者30天死亡率的预后因素的体积平均值:一个回顾性队列研究
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Fixed Volume or Fixed Pressure: A Murine Model of Hemorrhagic Shock
Published on: June 6, 2011
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Hanlim Choi1, Jin Young Lee2,3, Younghoon Sul4,5
1Department of Surgery, College of Medicine, Chungbuk National University, Cheongju, Republic of Korea.
Scientific reports
|February 16, 2024
概括
大型创伤患者的平均体积 (MCV) 水平可以预测死亡率. 最初的巨细胞瘤 (MCV ≥100 fL) 独立地与创伤幸存者的30天死亡率增加有关.
科学领域:
- 创伤护理的护理人员.
- 血液学 血液学 血液学
- 临床病理学 临床病理学
背景情况:
- 平均体积 (MCV) 是一种标准的红细胞测量.
- 在重创患者中MCV的预后价值仍在调查中.
研究的目的:
- 在患有重大创伤的患者中调查初始巨细胞瘤 (MCV ≥100 fL) 的临床影响.
- 为了确定宏细胞体是否独立地预测这个人群的30天死亡率.
主要方法:
- 对1218名重大创伤患者的单一中心回顾性审查 (伤害严重性评分≥16).
- 宏细胞和非宏细胞组之间的临床和实验室变量的比较.
- 考克斯回归分析以确定30天死亡率的预测因素.
主要成果:
- 宏细胞组 (n=199) 的初始低血压,输血率和30天死亡率高于非宏细胞组 (n=1019).
- 年龄,低血压,输血,贫血和巨细胞瘤与30天死亡率有显著的关联.
- 宏细胞瘤显示,30天死亡率的调整后危险比为1.4 (95% CI 1.01-1.94,p=0.046).
结论:
- 最初的巨细胞瘤是主要创伤患者30天死亡率的独立预测因素.
- 测量MCV可能有助于风险分层和创伤患者的管理.
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