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Updated: May 5, 2026

Multiplexed Immunofluorescence Analysis and Quantification of Intratumoral PD-1+ Tim-3+ CD8+ T Cells
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Multiplexed Immunofluorescence Analysis and Quantification of Intratumoral PD-1+ Tim-3+ CD8+ T Cells

Published on: February 8, 2018

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免疫检查点的纵向肠道微生物组变化 封锁治疗的晚期黑色素瘤 治疗的晚期黑色素瘤

Johannes R Björk1, Laura A Bolte2, Andrew Maltez Thomas3

  • 1Department of Gastroenterology and Hepatology, University of Groningen and University Medical Center Groningen, Groningen, the Netherlands. bjork.johannes@gmail.com.

Nature medicine
|February 16, 2024
PubMed
概括

了解免疫检查点阻塞 (ICB) 治疗期间肠道微生物组的变化对于优化癌症治疗至关重要. 这项研究揭示了与接受ICB治疗的黑色素瘤患者的治疗反应和生存相关的特定微生物模式.

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