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服细胞因子风暴:针对IL-6/IL-6α受体的小分子抑制剂

Komal Zia1, Mohammad Nur-E-Alam2, Aftab Ahmad3

  • 1H.E.J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, 75270, Pakistan.

Molecular diversity
|February 17, 2024
PubMed
概括

计算方法确定了针对IL-6的新型小分子,IL-6是细胞因子释放综合征 (CRS) 的关键驱动因素. 这些潜在的IL-6抑制剂为管理免疫疗法毒性和COVID-19等严重炎症状况提供了新的途径.

关键词:
在 COVID-19 疫情中,细胞因子释放综合征是什么介质素 6 介质素 6 介质素模拟MD的模拟方法蛋白质蛋白质相互作用

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