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Updated: Jul 2, 2025

Visualizing and Quantifying Pharmaceutical Compounds within Skin using Coherent Raman Scattering Imaging
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使用PBPK建模和模拟预测人类皮肤药物度:克洛贝塔索 propionate案例研究

William W van Osdol1, Jasmina Novakovic1, Maxime Le Merdy1

  • 1Simulations Plus, Incorporated, 42505 10th Street West, Lancaster, California, 93534, USA.

AAPS PharmSciTech
|February 17, 2024
PubMed
概括

计算机建模准确地预测局部药物输送,比如从奶油配方中获得的克洛贝塔索-17 (CP). 这种方法有助于通过了解皮肤透率和药物度来优化局部配方.

关键词:
PBPKK PBPK 的意思是什么意思关键的质量属性 关键的质量属性皮肤上的药理动力学建模和模拟的模型和模拟.专题配方设计 专题配方设计

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