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Updated: Jul 2, 2025

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技术驱动的神经退行性疾病的体外模型的进化

Eleonora De Vitis1, Antonella Stanzione1, Alessandro Romano2

  • 1CNR NANOTEC-Institute of Nanotechnology, Campus Ecotekn, via Monteroni, Lecce, 73100, Italy.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
|February 17, 2024
PubMed
概括

创新的器官芯片和3D打印技术为研究神经退行性疾病 (NDD) 提供了新的途径. 这些先进的模型克服了传统细胞培养的局限性,以更好地理解NDDs.

关键词:
生物墨水可以在生物墨水中使用.生物打印是一种生物打印技术.这种水凝是水凝.在体外模型模型中的体外模型.微型制造是指微型制造.神经退行性疾病的神经退行性疾病器官在芯片上的器官

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Embryonic and induced pluripotent stem cells are excellent models for disease research because of their ability to self-renew and differentiate into most cell types. Somatic cells from a patient are isolated and reprogrammed into induced pluripotent stem cells or iPSCs. These iPSCs are later differentiated into the desired cell type, which mirrors the diseased cell of the patient. In this way, disease models have been created for investigating diseases such as Down syndrome, type I diabetes,...
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