向髓氧化酶限制了髓细胞免疫抑制,增强了胰腺癌的免疫检查点治疗

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Angisha Basnet1, Kaitlyn M Landreth1, Remi Nohoesu1

  • 1Department of Microbiology, Immunology, and Cell Biology, School of Medicine, West Virginia University, 64 Medical Center Drive, Morgantown, WV, 26506, USA.

Cancer immunology, immunotherapy : CII
|February 17, 2024
PubMed
概括

骨髓氧化酶 (MPO) 在胰腺癌中驱动免疫抑制,阻碍免疫治疗. 在小鼠中抑制MPO通过减少免疫抑制细胞显著改善了对免疫检查点治疗的反应.

关键词:
免疫检查点疗法是免疫检查点疗法.骨髓状细胞是骨髓状细胞.骨髓氧化酶是什么?胰腺癌是一种癌症.

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