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化学基因CCL21通过影响中性粒细胞两极分化来决定肝细胞癌的免疫治疗反应

Wenxin Xu1, Jialei Weng1,2, Minghao Xu1,2

  • 1Department of Liver Surgery and Transplantation, Liver Cancer Institute, Zhongshan Hospital, Fudan University, Key Laboratory of Carcinogenesis and Cancer Invasion, Ministry of Education, Shanghai, 200032, People's Republic of China.

Cancer immunology, immunotherapy : CII
|February 17, 2024
PubMed
概括

化学基因C-C动机连接体21 (CCL21) 预测肝细胞癌 (HCC) 免疫治疗反应. 高的CCL21水平通过调节瘤微环境 (TME) 中的中性粒细胞来提高ICI的疗效.

关键词:
CCL2121 CCL21 CCL21 CCL21 CCL21 CCL21 CCL21 CCL21 CCL21肝细胞癌是肝细胞癌.免疫治疗是一种免疫疗法.中性粒细胞的两极分化在PD-1中使用PD-1.瘤微环境是一个微环境.

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