新生儿发作后的神经结果和死亡率与脑电图验证. 一个系统的审查
Hanna Westergren1, Mikael Finder2, Helena Marell-Hesla1
1Neuropaediatric Unit, Astrid Lindgren's Children's Hospital, Karolinska University Hospital and Dept of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden.
概括
经过脑电图确认的新生儿发作与各种神经学结果和死亡率有关. 报告结果的显著变化表明选择偏差,需要基于人口的研究来准确预测.
科学领域:
- 神经学 神经学
- 儿科 儿科 儿科
- 新生儿护理 新生儿护理
背景情况:
- 新生儿发作是新生儿护理的一个关键问题.
- 了解长期的神经结果和死亡率对于受影响的婴儿至关重要.
研究的目的:
- 系统地审查新生儿后神经学结果和新生儿发作经过脑电图验证的婴儿的死亡率.
- 在现有文献中识别报告结果的模式和变化.
主要方法:
- 在Medline,Embase和Web of Science的系统文献搜索.
- 选5518个记录,包括31项研究进行全文审查和数据提取.
- 包括的研究的质量评估,以评估可靠性.
主要成果:
- 报告的发病率 (5-84%),脑 (9-78%),智力障碍 (24-67%),发育迟缓 (10-67%) 和死亡率 (1-62%) 的广泛变化.
- 由于研究结果和措施的异质性,元分析是不可行的.
- 状态的队列显示出更高的新生儿后发病率 (46-84%).
结论:
- 结果的显著变化表明当前研究中存在相当大的选择偏差.
- 经过脑电图验证的新生儿发作具有广泛的神经后果.
- 建议基于人群的研究,以便在这个人群中更准确地预测结果.
相关概念视频
01:24Epilepsy and Seizures: Overview
Epilepsy is a chronic neurological disease marked by recurrent, unpredictable seizures. These seizures are caused by abnormal electrical discharges in the brain, leading to behavior, sensation, or consciousness alterations. They can also cause transient impairment of awareness, interfering with daily activities.
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
01:13Seizures: Classification
Epilepsy is primarily characterized by unpredictable seizures, either provoked by an identifiable factor, such as injury or illness, or unprovoked, occurring spontaneously without apparent cause.
Seizures are typically classified into two main categories: focal and generalized seizures.
Focal Seizures
Focal seizures originate from specific regions of the brain. These seizures are further sub-classified into two types:
Seizures are typically classified into two main categories: focal and generalized seizures.
Focal Seizures
Focal seizures originate from specific regions of the brain. These seizures are further sub-classified into two types:
01:20Seizures l: Introduction
Understanding seizures and epilepsy relies on key definitions that help in recognizing, classifying, and managing these disorders. These definitions provide a framework for recognizing, classifying, and managing seizure disorders.DefinitionsA seizure is a sudden, abnormal burst of electrical activity in the brain that can cause changes in awareness, movement, sensation, or behavior, depending on the area involved. Epilepsy is a chronic condition characterized by recurrent, unprovoked seizures,...