在等待肝移植的患者的预康复
Amine Benmassaoud1, Myriam Martel2, Franco Carli3
1Division of Gastroenterology and Hepatology, McGill University Health Centre, Montreal, Canada; Research Institute of the McGill University Health Centre, Montreal, Canada.
Transplantation reviews (Orlando, Fla.)
|February 17, 2024
概括
通过运动训练进行预康复似乎对肝移植候选人来说是可行的和安全的. 虽然显示身体功能有所改善,但需要进行更大规模的研究来证实其对移植结果的影响.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 移植医学 移植医学
- 老年病的医生 老年病的医生
背景情况:
- 虚弱,营养不良和肉症增加了肝移植 (LT) 患者的发病率和死亡率.
- 预康复旨在优化大手术前的身体健康,但其对LT候选人的影响还未得到充分研究.
研究的目的:
- 进行对预康复在等待LT患者的可行性,安全性和临床影响的范围审查.
- 为了评估临床参数在LT前或之后由于预康复干预而发生的变化.
主要方法:
- 从1946年到2023年11月的系统文献综述.
- 包括前性研究和在运动训练计划中对成年LT候选人的随机对照试验.
主要成果:
- 包括6项异质研究 (13-33名参与者);大多数是试点/可行性研究.
- 预康复干预是可行的 (54-100%的招募率) 和安全的 (9.2%的不良事件).
- 在峰值氧气消耗,工作量,6分钟步行距离和肌肉力量方面观察到改善;一项研究指出,移植后住院时间减少.
结论:
- 通过运动训练进行预康复对于等待LT的患者来说是可行的和安全的.
- 需要更高质量,更大规模的研究来验证其对移植前后结果的影响.
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