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Updated: Jul 2, 2025

Extraction and Quantification of Soluble, Radiolabeled Inositol Polyphosphates from Different Plant Species using SAX-HPLC
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Extraction and Quantification of Soluble, Radiolabeled Inositol Polyphosphates from Different Plant Species using SAX-HPLC

Published on: June 26, 2020

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在药物配方中使用新的HPLC-ICP-MS方法量化氧沙和岩醇相关化合物

Qiping Wu1, Jianmei Lv1, Feifan Xie1

  • 1Division of Biopharmaceutics and Pharmacokinetics, Xiangya School of Pharmaceutical Sciences, Central South University, Changsha 410013, China.

Journal of pharmaceutical and biomedical analysis
|February 17, 2024
PubMed
概括

这项研究开发了一种结构独立的高性能液体染色学与诱导合等离子体质谱学 (HPLC-ICP-MS) 方法相结合,用于量化氧沙和ioversol注射中的相关化合物. 新的HPLC-ICP-MS方法证明了准确和精确的量化,与标准方法相匹配.

关键词:
在HPLC中使用HPLC.在ICP-MS中,使用的是ICP-MS.定量分析是一种量化分析.相关的化合物 相关的化合物

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Inductively Coupled Plasma–Mass Spectrometry (ICP–MS): Overview

In inductively coupled plasma–mass spectrometry (ICP–MS), an inductively coupled plasma (ICP) torch is used as an atomizer and ionizer. Solid samples are dissolved and volatilized before being introduced into the high-temperature argon plasma, while solution samples are nebulized and passed through the high-temperature argon plasma. Plasma dissociates the analytes and ionizes their component atoms to form a mixture of positive ions and molecular species. The positive ions are then...
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Inductively Coupled Plasma-Mass Spectrometry (ICP-MS): Interferences

Inductively coupled plasma–mass spectrometry (ICP–MS) is a highly selective and sensitive technique for accurate elemental analysis. Though the analysis of ICP–MS mass spectra is comparatively straightforward, it is affected by spectroscopic and non-spectroscopic interferences. Spectroscopic interferences arise when the plasma contains ionic species with an m/z value the same as the analyte ion. Spectroscopic interference can be categorized as isobaric, polyatomic ions, and...
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