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在使用泛比诺斯塔特和干扰素α2a治疗期间选择表观遗传特权的HIV-1前病毒

Marie Armani-Tourret1, Ce Gao1, Ciputra Adijaya Hartana2

  • 1Ragon Institute of MGH, MIT and Harvard, Cambridge, MA 02139, USA.

Cell
|February 17, 2024
PubMed
概括

像panobinostat这样的潜伏逆转药物可以通过改变病毒储存器来帮助治愈HIV-1. 这项研究表明这些药物可以使HIV-1感染的细胞更容易受到免疫攻击,并可能加速病毒清除.

关键词:
艾滋病毒-1治愈艾滋病毒-1表观遗传学基因组乙化天生的免疫力整合场所干扰素其他:冲击并杀死病毒储存器

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