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在更年期后的骨质疏松症中,TNF-α通过上调TLR4促进骨质细胞亡

Hongwang Cui1, Ji Li1, Xiangtao Li1

  • 1Department of Emergency Surgery Trauma Medicine Center, The First Affiliated Hospital of Hainan Medical University, Haikou 570102, China.

Bone
|February 17, 2024
PubMed
概括

瘤坏死因子-α (TNF-α) 通过调节Toll类受体4 (TLR4) 的上升来促进绝经后骨质疏松症 (PMOP) 的骨质细胞亡. 抑制TLR4可以减少TNF-α诱导的细胞死亡,这表明PMOP的新治疗标.

关键词:
尸体灭 (Necroptosis) 是一种死亡的过程.骨质细胞是一种骨质细胞.绝经后的骨质疏松症 绝经后的骨质疏松症在TLR4中,这就是TNF-α.

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