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Updated: Jul 2, 2025

Examining BCL-2 Family Function with Large Unilamellar Vesicles
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Published on: October 5, 2012

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循环可以通过引入单一残留差异来区分BCL-2及其临床突变物与BCL-XL

Fengwei Li1, Junjie Liu2, Chao Liu3

  • 1Helmholtz International Lab, State Key Laboratory of Microbial Technology, Shandong University, Qingdao, 266237, China. lifengwei@sdu.edu.cn.

Nature communications
|February 17, 2024
PubMed
概括

新的循环 (CPs) 向BCL-2和BCL-XL蛋白质,提供一种新的抗癌机制. 这些可以克服对venetoclax的耐药性,并可能导致下一代癌症治疗药物.

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