维生素D和近视:一个审查
Chu-Yao Yu1, Li Dong1, Yi-Fan Li1
1Beijing Tongren Eye Center, Beijing Key Laboratory of Intraocular Tumor Diagnosis and Treatment, Beijing Ophthalmology & Visual Sciences Key Lab, Medical Artificial Intelligence Research and Verification Key Laboratory of the Ministry of Industry and Information Technology, Beijing Tongren Hospital, Capital Medical University, 1 Dong Jiao Min Lane, Beijing, 100730, China.
International ophthalmology
|February 18, 2024
概括
维生素D可能有助于预防近视的进展,特别是在儿童和青少年中,由于户外时间增加. 需要进一步的研究来澄清遗传联系和生物机制.
科学领域:
- 眼科医生 眼科 眼科
- 公共卫生 公共卫生
- 营养科学 营养科学
背景情况:
- 近视是一个全球性的健康问题,具有重大的社会经济影响.
- 环境因素,如户外时间,与近视发展有关.
- 维生素D对近视的作用正在调查中,可能与户外活动有关.
研究的目的:
- 审查和总结关于维生素D状态和近视之间的联系的研究.
- 探索流行病学,遗传学和机理学证据,将维生素D和近视联系起来.
- 评估维生素D作为预防近视的可修改因素的潜力.
主要方法:
- 对过去十年发表的研究进行系统审查.
- 对维生素D水平和近视的流行病学数据的分析.
- 检查遗传关联研究和拟议的生物机制.
主要成果:
- 流行病学研究表明,与户外时间相关的维生素D水平增加可能会延迟儿童和青少年近视的进展.
- 探索维生素D和近视相关性基因多态性的遗传研究尚未得出结论.
- 拟议的机制包括平衡和肌功能,但仍然在很大程度上未被证明.
结论:
- 维生素D可能会对近视的进展产生保护作用,特别是在年轻人群中.
- 进一步的研究对于阐明遗传联系和生物途径至关重要.
- 维生素D是预防或延迟近视的潜在可修改因素.
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