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在髓状细胞中,ATG5调节的CCL2/MCP-1产生有选择地调节抗疟疾CD4+ Th1反应

Yuanli Gao1, Suilin Chen1,2, Shiming Jiao1

  • 1Department of Pathogenic Biology, Army Medical University (Third Military Medical University), Chongqing, China.

Autophagy
|February 18, 2024
PubMed
概括

骨髓细胞中的ATG5缺乏会增强CD4+Th1细胞的反应,控制疟疾寄生虫的生长,独立于自. 这种机制涉及减少骨髓细胞亡和增加CCL2的产生,通过JAK2-STAT4通路促进Th1细胞活性.

关键词:
在ATG5中,它是ATG5.抗疟疾疫苗的使用在CCL2中,我们可以使用CCL2.CD4+ Th1 的反应.疟疾 疟疾 是一种疾病.骨髓状细胞是骨髓状细胞的组成部分.

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