患者焦虑的危险因素:一个元分析
Cailang Niu1, Penghong Li1, Xueqing Du1
1Third Hospital of Shanxi Medical University, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Taiyuan 030032, China.
Epilepsy & behavior : E&B
|February 18, 2024
概括
患者 (PWE) 的焦虑与女性性别,低社会经济地位,创伤史,抑郁和羞耻有关. 解决这些因素可以改善PWE的生活质量.
科学领域:
- 神经学 神经学
- 精神病学是一个精神病学.
- 流行病学 流行病学
背景情况:
- 是一种常见的神经疾病,需要对发作和相关的心理痛苦进行管理.
- 焦虑显著影响患者 (PWE) 的生活质量,但其危险因素仍未得到充分研究.
- 在PWE中识别焦虑风险因素对于有针对性的干预和改善患者结果至关重要.
研究的目的:
- 进行元分析,确定患者焦虑的重大风险因素 (PWE).
- 为开发策略提供证据,以减少焦虑发病率并提高PWE的生活质量.
主要方法:
- 在PubMed,Embase和Cochrane图书馆数据库中进行系统的文献搜索,截至2023年7月.
- 包括24项原始英语研究,包括5403名患者 (PWE).
- 使用几率比率 (ORs) 和95%置信区间 (CI) 评估风险因素影响的元分析.
主要成果:
- 在PWE中确定了焦虑的关键风险因素:女性性别 (OR=1.67),创伤史 (OR=2.53),抑郁症 (OR=5.45) 和与疾病相关的羞耻感 (OR=2.76).
- 其他重要因素包括未婚/离婚/寡妇身份 (OR=0.83),低社会经济地位 (OR=0.47),低教育程度 (OR=1.74),单疗法 (OR=0.49),抗药物 (AED) 的精神病副作用 (OR=2.45),以及自杀史 (OR=3.56).
结论:
- 女性性别,未婚状态,低社会经济地位,低学历,创伤史,单疗法,AED副作用,抑郁症,自杀史和羞耻感是PWE焦虑的重要危险因素.
- 进一步的研究是有必要的,以探索其他潜在的风险因素和验证发现.
- 建议进行更大规模的前性跨文化研究,因为包括的研究尺度的异质性和风险因素的全面性.
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