对于Covid-19患者的清醒倾向定位的最佳时间:来自两个中心的观察性研究的见解
Weiqing Zhang1, Yan He2, Qiuying Gu3
1Department of Critical Care Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China; Shanghai Jiao Tong University School of Nursing, Shanghai, China.
International journal of nursing studies
|February 18, 2024
概括
醒着的倾向性定位可以改善COVID-19患者的氧化. 最佳方案,包括SpO2:FiO2比率超过200和增加定位日,减少不良结果和死亡率.
科学领域:
- 关键护理医学 关键护理医学
- 呼吸系统医学 呼吸系统医学
- 在COVID-19研究研究中.
背景情况:
- 由于其简单性,起床倾向的定位被广泛用于改善氧化.
- 缺乏关于最佳治疗方案的共识,阻碍了对其有效性的理解.
- 这项研究调查了影响COVID-19患者的结果的因素,这些患者接受了清醒的倾向定位.
研究的目的:
- 为了确定在COVID-19患者中清醒易感定位的最佳方案.
- 确定影响患者结果的关键参数,包括时间,持续时间和坚持.
- 制定指导方针,以提高患者的舒适性和遵守醒着的倾向性定位.
主要方法:
- 一项回顾性观察性研究,涉及475名COVID-19肺炎患者.
- 从上海两家医院的电子医疗记录收集的数据.
- 使用ROC曲线和Cox回归来评估SpO2:FiO2比率和其他与28天结果相关的变量的统计分析.
主要成果:
- 在预测结果方面,在初始定位时,外周血液中氧和与吸入氧度比率 (SpO2:FiO2) 超过200是最有效的.
- 具有SpO2:FiO2 ≤200的患者出现显著更高的呼吸系统不良事件和死亡率.
- 更高的SpO2:FiO2,从第一次定位到入院的时间更长,更多的定位日,以及更好的坚持与改善的结果相关.
结论:
- 启动具有SpO2:FiO2比率> 200的清醒倾斜定位与更好的患者结果有关.
- 增加持续时间和坚持清醒易感定位协议可以显著降低死亡率和不良呼吸道事件.
- 优化清醒的时间和持续时间是管理COVID-19相关肺炎的关键.
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