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Updated: Jul 2, 2025

Injectable Supramolecular Polymer-Nanoparticle Hydrogels for Cell and Drug Delivery Applications
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Published on: February 7, 2021

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单剂和组合长效注射剂的加速和生物预测体外释放测试策略

Krutika Meena Harish Jain1, Tien Ho1, Susan Hoe2

  • 1Analytical Development and Operations, Gilead Sciences, 355 Lakeside Drive, Foster City, CA 94404, USA.

Journal of pharmaceutical sciences
|February 18, 2024
PubMed
概括

这项研究开发了新的体外释放测试 (IVRT) 方法,以预测长效注射剂 (LAI) 悬浮剂的性能. 这些经过验证的方法为临床前评估建立了体外-体内相关性 (IVIVC).

关键词:
在GastroPlus建模中使用GastroPlus.在体外/体内 (IVIVC) 相关性 (s)可以注射的 (s) 溶解长效的 长效的美国药典 (USP)

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