评估喘障碍和风险问卷中的有意义变化
William McCann1, Kevin R Murphy2, Robert S Zeiger3
1Allergy Partners, Asheville, North Carolina.
概括
建议将2的变化得分作为喘损伤和风险问卷 (AIRQ) 的最小重要差异 (MID). 这一分数表明患者的喘控制有意义地改善了.
科学领域:
- 肺部医学 肺部医学
- 临床评估工具 临床评估工具
- 喘管理 喘管理
背景情况:
- 喘损伤和风险问卷 (AIRQ) 是一个10项评估喘控制的工具,较低的分数表明更好的控制.
- 它包括7个损伤项目 (2周症状回忆) 和3个风险项目 (12个月恶化回忆).
- 一个后续的AIRQ版本使用3个月的回忆恶化.
研究的目的:
- 评估 AIRQ 随着时间的推移的响应能力.
- 为了确定AIRQ的最小重要差异 (MID).
主要方法:
- 分析了1070名喘患者 (≥12年) 的长度数据.
- 基于的方法将AIRQ得分变化与患者的全球变化印象,其他喘工具的MID和恶化的发生相关联.
- 使用12个月回忆 (基线,12个月) 和3个月回忆 (3,6,9个月) 评估了AIRQ得分.
主要成果:
- 一个"大大改善"的患者总体变化印象与AIRQ得分的相关性从-1.8降低到-2.0.
- AIRQ的变化与圣乔治呼吸道问卷和喘控制测试的既定MID保持一致.
- 基线AIRQ得分高2个点,12个月恶化的几率增加1.7 (95% CI,1.53-1.89).
结论:
- 建议以2的变化得分作为AIRQ的最小重要差异 (MID).
- 这一MID反映了喘控制的有意义的临床改善.
- AIRQ显示了对喘状况变化的反应能力.
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