在华盛顿州的注射器服务计划参与者中,急诊室利用和甲基胺过量症状
Noah D Frank1, Caleb J Banta-Green2,3, Brandon L Guthrie1
1Department of Epidemiology, School of Public Health, University of Washington, Seattle, Washington, USA.
Substance use & misuse
|February 18, 2024
概括
使用甲基胺 (PWUM) 的人经常出现过量症状. 建议寻求紧急护理,但因素尚不清楚. 非致命的阿片类药物过量服用增加了对甲基胺过量症状的急诊室访问.
科学领域:
- 公共卫生 公共卫生
- 成 药物 药物 药物 药物
- 紧急医疗 紧急医疗
背景情况:
- 甲胺过量服用会造成严重的心理和身体健康风险,包括精神病,心脏病发作和死亡.
- 建议使用甲基胺 (PWUM) 经历甲基胺过量症状 (MOS) 的人寻求紧急护理,但影响这一决定的因素尚不清楚.
研究的目的:
- 描述与PWUM中遇到MOS的急诊室/急诊室 (ER) 使用相关的因素.
- 评估ER用于MOS和非致命的阿片类药物过量服用,多重物质使用和败血症之间的关联.
主要方法:
- 利用了2021年华盛顿州注射器服务计划 (SSP) 健康调查 (N=955) 的数据.
- 采用波桑回归来分析用于甲基胺使用的ER利用与经历MOS的PWUM中各种共变量之间的关联.
主要成果:
- 甲基胺的使用率很高 (86%在过去3个月).
- 37%的PWUM报告在前三个月中至少经历了一次MOS.
- 非致命的阿片类药物过量使用 (APR=2.04),联合海洛因/甲基胺使用 (APR=1.98),和败血症 (APR=2.07) 与MOS的ER利用有显著的关联.
结论:
- 在华盛顿州的SSP用户中,甲基胺使用和MOS普遍存在.
- 最近非致命的阿片类药物过量服用是MOS的ER利用的重要预测因素.
- 查阿片类药物使用障碍和提供降低危害物资 (纳洛,MOUD) 对于患有MOS的患者至关重要.
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