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果糖调节酸通路,并诱导Kupffer细胞中的炎症和分离表型

Mareca Lodge1, Grace Scheidemantle1, Victoria R Adams1

  • 1Department of Molecular and Structural Biochemistry, NC State University, Raleigh, NC, USA.

Scientific reports
|February 18, 2024
PubMed
概括

摄入高的果糖会损害肝脏的健康,降低库普弗细胞的活力,增加炎症. 这项研究揭示了果糖对巨细胞功能的影响,并促进纤维化基因表达,有助于非酒精性脂肪肝疾病 (NAFLD) 的进展.

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