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相关概念视频

Neurulation01:30

Neurulation

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Neurulation is the embryological process which forms the precursors of the central nervous system and occurs after gastrulation has established the three primary cell layers of the embryo: ectoderm, mesoderm, and endoderm. In humans, the majority of this system is formed via primary neurulation, in which the central portion of the ectoderm—originally appearing as a flat sheet of cells—folds upwards and inwards, sealing off to form a hollow neural tube. As development proceeds, the...
41.9K

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Live Imaging of Primary Cerebral Cortex Cells Using a 2D Culture System
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从祖细胞的角度来看,灵长类新皮质的发展和进化.

Colette Dehay1, Wieland B Huttner2

  • 1Université Claude Bernard Lyon 1, Inserm, Stem Cell and Brain Research Institute U1208, F-69500 Bron, France.

Development (Cambridge, England)
|February 19, 2024
PubMed
概括

灵长类动物新皮质大小的进化性增加,特别是上层神经元,与外腹下区域的祖先扩张有关. 这些祖先的人类特异性遗传变化可能解释了与尼安德特人的认知差异.

科学领域:

  • 发育生物学是发展生物学.
  • 进化生物学是进化的生物学.
  • 神经科学是一个神经科学.

背景情况:

  • 新皮质的大小是由神经元生成决定的,灵长类的进化显示了与认知收益相关的上层神经元的增加.
  • 外腹腔下部区域 (OSVZ) 对于灵长类新皮层神经生成至关重要.

结论:

  • 灵长类动物上层神经元的进化扩张是由OSVZ祖先放大驱动的.
  • 神经祖先中人类特有的遗传变化为我们提供了关于认知进化和与尼安德特人的差异的见解.
关键词:
皮层的发展 皮层的发展进化 进化 进化 进化 进化 进化 进化人类 人类 人类 人类 人类灵长类动物中的灵长类动物

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