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Updated: Jul 2, 2025

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有针对性的蛋白质降解直接涉及溶解体或蛋白质体

Jiseong Kim1,2, Insuk Byun1,2, Do Young Kim3

  • 1Department of Biochemistry & Molecular Biology, Seoul National University College of Medicine, Seoul 03080, Korea. minjlee@snu.ac.kr.

Chemical Society reviews
|February 19, 2024
PubMed
概括

向蛋白质降解 (TPD) 提供了控制蛋白质功能的新方法,包括超越蛋白质分解向嵌合体 (PROTACs) 的新策略. 这些方法扩大了以前无法治疗的目标的治疗选择.

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