在研究表观遗传对运动反应的全球科学趋势:一本书法分析分析
Huijuan Wu1,2, Yue Hu1,2, Cai Jiang1,2
1College of Rehabilitation Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, 350122, Fujian, China.
Heliyon
|February 19, 2024
概括
运动通过表观遗传修饰显著影响基因表达,例如DNA甲基化和非编码RNA. 本综述分析了运动表观遗传学的研究趋势和热点.
科学领域:
- 表观遗传学和运动生理学
- 基因组学和分子生物学
背景情况:
- 表观遗传修饰在调节基因表达方面发挥着至关重要的作用.
- 众所周知,运动会诱导显著的生理适应,可能由表观遗传变化介导.
研究的目的:
- 综合分析表观遗传修饰对运动诱导的基因表达变化的适应性反应.
- 确定运动表观遗传学领域的研究热点和新兴趋势.
主要方法:
- 从PubMed和Web of Science核心集合系统地检索文献,直到2023年10月.
- 使用CiteSpace进行图书统计分析,探索出版趋势,有影响力的作者,机构和国家.
- 关键词分析以确定研究热点.
主要成果:
- 总共有1910个出版物 (1399篇文章,511篇评论) 被分析.
- 基因甲基化 (512),基因素修饰 (224),非编码RNA (772) 是表观遗传学研究的关键领域.
- 美国在出版物方面处于领先地位,加利福尼亚大学系统是最具生产力的机构,蒂亚哥·费尔南德斯是出版物最多的作者.
- 研究热点包括心血管疾病,癌症,骨肌肉发育和代谢综合征.
结论:
- 本文献分析详细概述了运动表观遗传学研究当前的现状.
- 了解这些作为运动反应的表观遗传修饰,为疾病机制和治疗策略提供了宝贵的见解.
- 这些发现突出了未来在运动和表观遗传科学方面的研究和合作的关键领域.
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