对药物使用障碍的民事承诺法律对阿片类药物过量死亡的影响
Phillip Cochran1, Peter S Chindavong1, Jurian Edelenbos1
1Alabama College of Osteopathic Medicine, Dothan, AL, United States.
Frontiers in psychiatry
|February 19, 2024
概括
对物质使用障碍 (SUD) 的民事承诺 (CC) 法律对阿片类药物过量死亡率 (OODR) 总体而言没有显著影响. 然而,在COVID后,拥有CC SUD法律的州出现了显著的OODR增加.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 药物使用障碍研究 药物使用障碍研究
背景情况:
- 在美国,阿片类药物过量死亡率 (OODR) 仍然是一个关键的公共卫生问题.
- 作为解决阿片类药物危机的措施,一些州实施了针对物质使用障碍 (SUD) 的民事承诺 (CC) 法律.
研究的目的:
- 分析CC SUD法律对2010年至2021年美国OODR的影响.
- 为了比较COVID-19大流行之前和之后的CC SUD法律和没有CC SUD法律的州的OODR趋势.
主要方法:
- 使用CDC WONDER数据集 (2010-21) 的回顾性研究设计.
- 使用ICD-10代码对年龄调整的OODR进行分析.
- 在拥有和没有CC SUD法律的州之间进行统计比较 (t-test,ANOVA).
主要成果:
- 从2010年到21年,在拥有和没有CC SUD法律的州之间,年平均年龄调整的OODR没有显著差异.
- 在COVID前的时代 (2010-19),CC SUD法律对OODR没有影响.
- 在后COVID时代 (2020-21年) 中,拥有CC SUD法律的州在OODR中比没有法律的州大幅增加 (p=0.032).
- 在COVID后,OODR在CC SUD法律和没有CC SUD法律的州都以更快的速度增长.
结论:
- 在COVID后拥有CC SUD法律的州,高年龄调整的OODR可能与法律实施时间,医生意识或使用不足有关.
- 诸如最近颁布的法律,缺乏复发数据和过量减少差异等因素影响了OODR.
- 需要进一步的研究来了解影响OODR的复杂因素以及CC SUD法律的长期影响.
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