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Updated: Jul 2, 2025

HOX Loci Focused CRISPR/sgRNA Library Screening Identifying Critical CTCF Boundaries
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Published on: March 31, 2019

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稀少的CBX2核化了许多Polycomb蛋白质,以促进Polycomb目标基因的选择性异染色化

Steven Ingersoll1, Abby Trouth2, Xinlong Luo3

  • 1Department of Chemistry, University of Colorado Denver, Denver, CO 80217-3364, USA.

bioRxiv : the preprint server for biology
|February 19, 2024
PubMed
概括

低丰富度的CBX2蛋白质核聚抑制复合体 (PRC) 凝聚物,控制可选的异色素蛋白形成和细胞分化. 这项研究揭示了通过液-液相分离 (LLPS) 调节异色素的新机制.

关键词:
这就是CBX2的CBX2.H3K27me3 在线阅读在PRC1中,在 PRC2 中,PRC2 是 PRC2 的第一个类型.多重复合的多重复合.在这种情况下,染色染色素构成性的 异色染色素.选择性的异色染色.液态-液态相隔离方法 液态相隔离方法活细胞单分子追踪核化的核化.单个分子成像技术

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